Eremomycin
| Code | Size | Price |
|---|
| TAR-T27280-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Eremomycin, an antibiotic, can be used intramuscularly due to low toxicity.
CAS:
110865-90-2
Formula:
C73H91ClN10O26
Molecular Weight:
1560.03
Purity:
0.98
SMILES:
CN[C@H](CC(C)C)C(=O)N[C@@H]1[C@H](O)c2ccc(Oc3cc4cc(OC5=CC=C(CC5)[C@@H](O[C@H]5C[C@](C)(N)[C@@H](O)[C@H](C)O5)[C@@H]5NC(=O)[C@@H](NC(=O)[C@@H]4NC(=O)[C@H](CC(N)=O)NC1=O)c1ccc(O)c(c1)-c1c(O)cc(O)cc1[C@H](NC5=O)C(O)=O)c3O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O[C@H]1C[C@](C)(N)[C@@H](O)[C@H](C)O1)c(Cl)c2
References
1. Bychkova EN, Korolev AM, Olsufyeva EN, Mirchink EP, Isakova EB. [Design of Novel Carboxamides of Eremomycin and Vancomycin with 4- or 3-Amino Methyl Phenyl Boric Acid and Their Investigation]. Antibiot Khimioter. 2015;60(9-10):7-11. Russian. PubMed PMID: 27141632.
2. Nikitina YK, Ali I, Asnin LD. Adsorption of aqueous organic mixtures on a chiral stationary phase with bound antibiotic eremomycin. J Chromatogr A. 2014 Oct 10;1363:71-8. doi: 10.1016/j.chroma.2014.08.062. Epub 2014 Aug 26. PubMed PMID: 25182859.
3. Chang J, Zhou H, Preobrazhenskaya M, Tao P, Kim SJ. The Carboxyl Terminus of Eremomycin Facilitates Binding to the Non-d-Ala-d-Ala Segment of the Peptidoglycan Pentapeptide Stem. Biochemistry. 2016 Jun 21;55(24):3383-91. doi: 10.1021/acs.biochem.6b00188. Epub 2016 Jun 7. PubMed PMID: 27243469.
4. Miroshnikova OV, Berdnikova TF, Olsufyeva EN, Pavlov AY, Reznikova MI, Preobrazhenskaya MN, Ciabatti R, Malabarba A, Colombo L. A modification of the N-terminal amino acid in the eremomycin aglycone. J Antibiot (Tokyo). 1996 Nov;49(11):1157-61. PubMed PMID: 8982345.