Flerobuterol HCl
| Code | Size | Price |
|---|
| TAR-T27331-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T27331-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T27331-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Flerobuterol is a β adrenergic receptor agonist potentially for the treatment of major depressive disorder. Flerobuterol enhances serotonergic neurotransmission. Flerobuterol acutely increases 5-HT synthesis, in part, through an elevation of brain Trp availability.
CAS:
82101-08-4
Formula:
C12H19ClFNO
Molecular Weight:
247.74
Purity:
0.98
SMILES:
Cl.CC(C)(C)NCC(O)c1ccccc1F
References
1. Morin D, Sapena R, Tillement JP, Urien S. Evidence for different interactions between beta(1)- and beta(2)-adrenoceptor subtypes with adenylyl cyclase in the rat brain: a concentration-response study using forskolin. Pharmacol Res. 2000 Apr;41(4):435-43. PubMed PMID: 10704268.
2. Tsuiki K, Blier P, Diksic M. Effect of the beta-adrenoceptor agonist flerobuterol on serotonin synthesis in the rat brain. Biochem Pharmacol. 2000 Mar 15;59(6):673-9. PubMed PMID: 10677584.
3. Toet AE, te Biesebeek JD, Vleeming W, Wemer J, Meulenbelt J, de Wildt DJ. Reduced survival after isoprenaline/dopamine in d,l-propranolol intoxicated rats. Hum Exp Toxicol. 1996 Feb;15(2):120-8. PubMed PMID: 8645502.
4. Zini R, Morin D, Martin P, Puech AJ, Tillement JP. Interactions of flerobuterol, an antidepressant drug candidate, with beta adrenoceptors in the rat brain. J Pharmacol Exp Ther. 1991 Oct;259(1):414-22. PubMed PMID: 1681091.