FP-21399 (Sodium)
| Code | Size | Price |
|---|
| TAR-T27356-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
FP-21399, an HIV fusion inhibitor, is used potentially for the treatment of HIV infection.
CAS:
170020-61-8
Formula:
C40H20Cl4N6Na4O16S4
Molecular Weight:
1202.63
Purity:
0.98
SMILES:
[Na+].[Na+].[Na+].[Na+].Oc1c(N=Nc2ccc(cc2)N=Nc2c(O)c3c(NC(=O)c4cccc(Cl)c4Cl)cc(cc3cc2S([O-])(=O)=O)S([O-])(=O)=O)c(cc2cc(cc(NC(=O)c3ccc(Cl)cc3Cl)c12)S([O-])(=O)=O)S([O-])(=O)=O
References
1. Poli G, Vicenzi E. FP-21399 (Lexigen Pharmaceuticals). IDrugs. 2001 Nov;4(11):1293-5. PubMed PMID: 15942835.
2. Yamaguchi N, Dahl T, Ono M, Gillies S. Liquid chromatographic determination of FP-21399 in plasma of patients with HIV infection. J Pharm Biomed Anal. 2000 Sep;23(4):715-22. PubMed PMID: 10975247.
3. Dezube BJ, Dahl TA, Wong TK, Chapman B, Ono M, Yamaguchi N, Gillies SD, Chen LB, Crumpacker CS. A fusion inhibitor (FP-21399) for the treatment of human immunodeficiency virus infection: a phase I study. J Infect Dis. 2000 Aug;182(2):607-10. PubMed PMID: 10915097.
4. Zhang JL, Choe H, Dezube BJ, Farzan M, Sharma PL, Zhou XC, Chen LB, Ono M, Gillies S, Wu Y, Sodroski JG, Crumpacker CS. The bis-azo compound FP-21399 inhibits HIV-1 replication by preventing viral entry. Virology. 1998 May 10;244(2):530-41. PubMed PMID: 9601521.