GW-813893

TargetMol
Product Code: TAR-T27514
Supplier: TargetMol
CodeSizePrice
TAR-T27514-5mg5mg£1,171.00
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Quantity:
TAR-T27514-50mg50mg£2,303.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T27514-100mg100mg£3,042.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

1 / 1

Further Information

Bioactivity:
GW-813893 is a potent, selective and orally active factor Xa inhibitor. GW813893 inhibited FXa and prothrombinase activity with a Ki of 4.0 nM and 9.7 nM, respectively.
CAS:
478644-12-1
Formula:
C17H22ClN3O5S2
Molecular Weight:
447.95
Purity:
0.98
SMILES:
C[C@H](N1CC[C@H](NS(=O)(=O)C=Cc2ccc(Cl)s2)C1=O)C(=O)N1CCOCC1

References

1. Abboud MA, Needle SJ, Burns-Kurtis CL, Valocik RE, Koster PF, Amour AJ, Chan C, Brown D, Chaudry L, Zhou P, Patikis A, Patel C, Pateman AJ, Young RJ, Watson NS, Toomey JR. Antithrombotic potential of GW813893: a novel, orally active, active-site directed factor Xa inhibitor. J Cardiovasc Pharmacol. 2008 Jul;52(1):66-71. doi: 10.1097/FJC.0b013e31817e9b9e. PubMed PMID: 18645410.