TargetMol

ICI 192605

Product Code:
 
TAR-T27575
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T27575-5mg5mg£930.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T27575-50mg50mg£1,821.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T27575-100mg100mg£2,319.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
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Further Information

Bioactivity:
ICI 192605 is a potent thromboxane A2 receptor (TP receptor) antagonist.
CAS:
117621-64-4
Formula:
C22H23ClO5
Molecular Weight:
402.87
Purity:
0.98
SMILES:
OC(=O)CCC=CC[C@@H]1CO[C@@H](O[C@@H]1c1ccccc1O)c1ccccc1Cl

References

1. Brown GR, Foubister AJ, Hudson JA. Improved synthetic routes to the novel thromboxane receptor antagonist ICI 192605: activity of synthetic 1,3-dioxane intermediates. J Pharm Pharmacol. 1990 Jan;42(1):53-5. PubMed PMID: 1969951. 2. Brewster AG, Brown GR, Foubister AJ, Jessup R, Smithers MJ. The synthesis of a novel thromboxane receptor antagonist 4(Z)-6-(2-o-chlorophenyl-4-o-hydroxyphenyl-1,3-dioxan-cis-5-yl) hexenoic acid ICI 192605. Prostaglandins. 1988 Aug;36(2):173-8. PubMed PMID: 2973084.