TargetMol

Ifetroban

Product Code:
 
TAR-T27588
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T27588-5mg5mg£1,894.00
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TAR-T27588-50mg50mg£3,749.00
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Quantity:
TAR-T27588-100mg100mg£5,211.00
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This product comes from: United States.
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Further Information

Bioactivity:
Ifetroban is a potent and selective TxA2/PGH2 receptor antagonist.
CAS:
143443-90-7
Formula:
C25H32N2O5
Molecular Weight:
440.54
Purity:
0.98
SMILES:
[H][C@@]12CCC(O1)C(C2Cc1ccccc1CCC(O)=O)c1nc(co1)C(=O)NCCCCC

References

1. Pestel S, Nath A, Jungermann K, Schieferdecker HL. Inhibition of prostaglandin D2 clearance in rat hepatocytes by the thromboxane receptor antagonists daltroban and ifetroban and the thromboxane synthase inhibitor furegrelate. Biochem Pharmacol. 2003 Aug 15;66(4):643-52. PubMed PMID: 12906929. 2. Rosenfeld L, Grover GJ, Stier CT Jr. Ifetroban sodium: an effective TxA2/PGH2 receptor antagonist. Cardiovasc Drug Rev. 2001 Summer;19(2):97-115. Review. PubMed PMID: 11484065. 3. Dockens RC, Santone KS, Mitroka JG, Morrison RA, Jemal M, Greene DS, Barbhaiya RH. Disposition of radiolabeled ifetroban in rats, dogs, monkeys, and humans. Drug Metab Dispos. 2000 Aug;28(8):973-80. PubMed PMID: 10901709. 4. Katz SD, Radin M, Graves T, Hauck C, Block A, LeJemtel TH. Effect of aspirin and ifetroban on skeletal muscle blood flow in patients with congestive heart failure treated with Enalapril. Ifetroban Study Group. J Am Coll Cardiol. 1999 Jul;34(1):170-6. PubMed PMID: 10400007.