Imiloxan

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TargetMol
Product Code: TAR-T27599
Supplier: TargetMol
CodeSizePrice
TAR-T27599-5mg5mg£1,091.00
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Quantity:
TAR-T27599-50mg50mg£2,143.00
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Quantity:
TAR-T27599-100mg100mg£2,801.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
Imiloxan, an α2 adrenergic receptor antagonist, is used potentially for the treatment of major depressive disorder.
CAS:
81167-16-0
Formula:
C14H16N2O2
Molecular Weight:
244.294
Purity:
0.98
SMILES:
CCn1ccnc1CC1COc2ccccc2O1

References

1. Fitch WL, Chen Y, Liu L, Paehler A, Young M. Application of modern drug metabolism structure determination tools and assays to the in vitro metabolism of imiloxan. Drug Metab Lett. 2010 Apr;4(2):77-87. PubMed PMID: 20446913. 2. Takano Y, Takano M, Yaksh TL. The effect of intrathecally administered imiloxan and WB4101: possible role of alpha 2-adrenoceptor subtypes in the spinal cord. Eur J Pharmacol. 1992 Sep 4;219(3):465-8. PubMed PMID: 1358645. 3. Rush WR, Hall DJ, Graham DJ, Selby IA. The metabolism of imiloxan hydrochloride in healthy male volunteers. Xenobiotica. 1992 Feb;22(2):237-46. PubMed PMID: 1352928. 4. Michel AD, Loury DN, Whiting RL. Assessment of imiloxan as a selective alpha
2B-adrenoceptor antagonist. Br J Pharmacol. 1990 Mar;99(3):560-4. PubMed PMID: 1970500; PubMed Central PMCID: PMC1917331.