TargetMol

Iodiconazole

Product Code:
 
TAR-T27619
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T27619-5mg5mg£850.00
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Quantity:
TAR-T27619-50mg50mg£1,661.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T27619-100mg100mg£2,079.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
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This product comes from: United States.
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Further Information

Bioactivity:
Iodiconazole, an azole antifungal, is used potentially for the treatment of fungal infection.
CAS:
887138-63-8
Formula:
C19H19F2IN4O
Molecular Weight:
484.289
Purity:
0.98
SMILES:
CN(Cc1ccc(I)cc1)CC(O)(Cn1cncn1)c1ccc(F)cc1F

References

1. Zhao H, She XD, Yu XX, Fu JF, Chen Y, Tian Y, Zhang ZJ. Quantification of iodiconazole by LC-MS/MS, a new topical transdermal cream, in dermatophytosis patients' plasma. Bioanalysis. 2015;7(7):895-905. doi: 10.4155/bio.15.19. PubMed PMID: 25932523. 2. Jiang Z, Wang Y, Wang W, Wang S, Xu B, Fan G, Dong G, Liu Y, Yao J, Miao Z, Zhang W, Sheng C. Discovery of highly potent triazole antifungal derivatives by heterocycle-benzene bioisosteric replacement. Eur J Med Chem. 2013 Jun;64:16-22. doi: 10.1016/j.ejmech.2013.04.025. Epub 2013 Apr 17. PubMed PMID: 23643831. 3. Sun N, Xie Y, Sheng C, Cao Y, Zhang W, Chen H, Fan G. In vivo pharmacokinetics and in vitro antifungal activity of iodiconazole, a new triazole, determined by microdialysis sampling. Int J Antimicrob Agents. 2013 Mar;41(3):229-35. doi: 10.1016/j.ijantimicag.2012.10.020. Epub 2013 Jan 6. PubMed PMID: 23298433. 4. Xiong HP, Gao SH, Li CT, Wu ZJ. (2RS)-2-(2,4-Difluoro-phen-yl)-1-[(4-iodo-benz-yl)(meth-yl)amino]-3-(1H-1,2,4-tri -azol-1-yl)propan-2-ol. Acta Crystallogr Sect E Struct Rep Online. 2012 Aug 1;68(Pt 8):o2447-8. doi: 10.1107/S160053681203139X. Epub 2012 Jul 14. PubMed PMID: 22904893; PubMed Central PMCID: PMC3414360.