K-111
Code | Size | Price |
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TAR-T27706-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T27706-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T27706-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
K-111 is a PPAR alpha agonist. K-111 improves insulin resistance, reducing bodyweight, and ameliorating atherogenic dyslipidemia.
CAS:
221564-97-2
Formula:
C18H25Cl3O2
Molecular Weight:
379.75
Purity:
0.98
SMILES:
OC(=O)C(Cl)(Cl)CCCCCCCCCCc1ccc(Cl)cc1
References
1. Martins DE, Medeiros VP, Demerov GF, Accardo CM, Paredes-Gamero EJ, Wajchenberg M, Reginato RD, Nader HB, Puertas EB, Faloppa F. Ionic and biochemical characterization of bovine intervertebral disk. Connect Tissue Res. 2016 May;57(3):212-9. doi: 10.3109/03008207.2016.1140751. PubMed PMID: 26942772.
2. Parsons SP, Huizinga JD. Transient outward potassium current in ICC. Am J Physiol Gastrointest Liver Physiol. 2010 Mar;298(3):G456-66. doi: 10.1152/ajpgi.00340.2009. PubMed PMID: 20056898.
3. Drew BG, Calkin AC. Drug evaluation: K-111, an insulin-sensitizing peroxisome proliferator-activated receptor alpha agonist. Curr Opin Investig Drugs. 2007 Apr;8(4):324-30. Review. PubMed PMID: 17458183.
4. Murakami K, Bujo H, Unoki H, Saito Y. Effect of PPARalpha activation of macrophages on the secretion of inflammatory cytokines in cultured adipocytes. Eur J Pharmacol. 2007 Apr 30;561(1-3):206-13. PubMed PMID: 17320860.