KRM-II-81
Code | Size | Price |
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TAR-T27744-5mg | 5mg | £1,091.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T27744-50mg | 50mg | £2,143.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T27744-100mg | 100mg | £2,801.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
KRM-II-81 is a γ?Aminobutyric Acid Type A (GABAA) Receptor Ligand. KRM-II-81 exhibits improved anxiolytic-like effects in a mouse marble burying assay and a rat Vogel conflict test.
CAS:
2014348-91-3
Formula:
C21H13N5O
Molecular Weight:
351.369
Purity:
0.98
SMILES:
C#Cc1ccc-2c(c1)C(=NCc1c(ncn-21)-c1cnco1)c1ccccn1
References
1. Synthesis and Characterization of a Novel ?-Aminobutyric Acid Type A (GABAA) Receptor Ligand That Combines Outstanding Metabolic Stability, Pharmacokinetics, and Anxiolytic Efficacy Michael M. Poe, Kashi Reddy Methuku, Guanguan Li, Ashwini R. Verma, Kelly A. Teske, Douglas C. Stafford, Leggy A. Arnold, Jeffrey W. Cramer, Timothy M. Jones, Rok Cerne, Michael J. Krambis, Jeffrey M. Witkin, Enrique Jambrina, Sabah Rehman, Margot Ernst, James M. Cook, and Jeffrey M. Schkeryantz Publication Date (Web): November 11, 2016 (Brief Article) doi: 10.1021/acs.jmedchem.6b01332