Lifarizine
Code | Size | Price |
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TAR-T27830-1mg | 1mg | £188.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T27830-5mg | 5mg | £352.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T27830-10mg | 10mg | £496.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T27830-25mg | 25mg | £760.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T27830-50mg | 50mg | £1,018.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T27830-100mg | 100mg | £1,348.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
Lifarizine is a calcium and sodium channel antagonist. Lifarizine (RS-87476) shows neuroprotective efficacy in a simplified rat survival model of 2 vessel occlusion.
CAS:
119514-66-8
Formula:
C29H32N4
Molecular Weight:
436.603
Pathway:
Membrane transporter/Ion channel|Metabolism
Purity:
0.98
SMILES:
Cc1[nH]c(nc1CN1CCN(CC1)C(c1ccccc1)c1ccccc1)-c1ccc(C)cc1
Target:
Calcium Channel
References
1. Spedding M. Reasons why stroke trials underestimate the neuroprotective effects of drugs. Stroke. 2002 Jan;33(1):324-5. PubMed PMID: 11779937.
2. Mestre M, Djellas Y, Carriot T, Cavero I. Frequency-independent blockade of cardiac Na+ channels by riluzole: comparison with established anticonvulsants and class I anti-arrhythmics. Fundam Clin Pharmacol. 2000 Mar-Apr;14(2):107-17. PubMed PMID: 10796057.
3. Cramer WC, Toorop GP. Focal cerebral ischemia in the mouse: hypothermia and rapid screening of drugs. Gen Pharmacol. 1998 Feb;30(2):195-200. PubMed PMID: 9502174.
4. Lees KR. Cerestat and other NMDA antagonists in ischemic stroke. Neurology. 1997 Nov;49(5 Suppl 4):S66-9. Review. PubMed PMID: 9371155.