LMI-1195
| Code | Size | Price |
|---|
| TAR-T27840-5mg | 5mg | £930.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T27840-50mg | 50mg | £1,821.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T27840-100mg | 100mg | £2,319.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
LMI-1195 is a 18F-labeled ligand for the norepinephrine transporter. LMI-1195 is used for mapping cardiac nerve terminals in vivo using positron emission tomography (PET).
CAS:
1037359-47-9
Formula:
C11H15BrFN3O
Molecular Weight:
303.166
Purity:
0.98
SMILES:
NC(=N)NCc1ccc(OCCC[18F])c(Br)c1
References
1. Werner RA, Rischpler C, Onthank D, Lapa C, Robinson S, Samnick S, Javadi M, Schwaiger M, Nekolla SG, Higuchi T. Retention Kinetics of the 18F-Labeled Sympathetic Nerve PET Tracer LMI1195: Comparison with 11C-Hydroxyephedrine and 123I-MIBG. J Nucl Med. 2015 Sep;56(9):1429-33. doi: 10.2967/jnumed.115.158493. PubMed PMID: 26182969.
2. Yu M, Bozek J, Lamoy M, Guaraldi M, Silva P, Kagan M, Yalamanchili P, Onthank D, Mistry M, Lazewatsky J, Broekema M, Radeke H, Purohit A, Cdebaca M, Azure M, Cesati R, Casebier D, Robinson SP. Evaluation of LMI1195, a novel 18F-labeled cardiac neuronal PET imaging agent, in cells and animal models. Circ Cardiovasc Imaging. 2011 Jul;4(4):435-43. doi: 10.1161/CIRCIMAGING.110.962126. PubMed PMID: 21555377.
3. Gaertner FC, Wiedemann T, Yousefi BH, Lee M, Repokis I, Higuchi T, Nekolla SG, Yu M, Robinson S, Schwaiger M, Pellegata NS. Preclinical evaluation of 18F-LMI1195 for in vivo imaging of pheochromocytoma in the MENX tumor model. J Nucl Med. 2013 Dec;54(12):2111-7. doi: 10.2967/jnumed.113.119966. PubMed PMID: 24136933.
4. Higuchi T, Yousefi BH, Kaiser F, G?rtner F, Rischpler C, Reder S, Yu M, Robinson S, Schwaiger M, Nekolla SG. Assessment of the 18F-labeled PET tracer LMI1195 for imaging norepinephrine handling in rat hearts. J Nucl Med. 2013 Jul;54(7):1142-6. doi: 10.2967/jnumed.112.104232. PubMed PMID: 23670901.