TargetMol

Losigamone

Product Code:
 
TAR-T27845
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T27845-1mg1mg£131.00
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TAR-T27845-5mg5mg£214.00
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TAR-T27845-10mg10mg£287.00
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TAR-T27845-25mg25mg£477.00
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TAR-T27845-50mg50mg£617.00
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TAR-T27845-100mg100mg£866.00
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Further Information

Bioactivity:
Losigamone, GABA receptor agonist, is used potentially for the treatment of partial seizures.
CAS:
112856-44-7
Formula:
C12H11ClO4
Molecular Weight:
254.67
Pathway:
Membrane transporter/Ion channel|Neuroscience
Purity:
0.98
SMILES:
COC1=CC(=O)O[C@@H]1[C@@H](O)c1ccccc1Cl
Target:
GABA Receptor

References

1. Willmore LJ. Losigamone. Dr Willmar Schwabe. Curr Opin Investig Drugs. 2001 Dec;2(12):1763-6. Review. PubMed PMID: 11892943. 2. Perucca E, Bialer M. The clinical pharmacokinetics of the newer antiepileptic drugs. Focus on topiramate, zonisamide and tiagabine. Clin Pharmacokinet. 1996 Jul;31(1):29-46. Review. PubMed PMID: 8827398. 3. Biber A, Dienel A. Pharmacokinetics of losigamone, a new antiepileptic drug, in healthy male volunteers. Int J Clin Pharmacol Ther. 1996 Jan;34(1):6-11. PubMed PMID: 8688997. 4. Dimpfel W, Chatterjee SS, N?ldner M, Ticku MK. Effects of the anticonvulsant losigamone and its isomers on the GABAA receptor system. Epilepsia. 1995 Oct;36(10):983-9. PubMed PMID: 7555962.