LSP4-2022
Code | Size | Price |
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TAR-T27857-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T27857-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T27857-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
LSP4-2022, a mGlu4 selective agonist, increases behavioral despair in mouse models of antidepressant action.
CAS:
1413405-33-0
Formula:
C13H18NO8P
Molecular Weight:
347.26
Purity:
0.98
SMILES:
N[C@@H](CCP(O)(=O)C(O)c1ccc(OCC(O)=O)cc1)C(O)=O
References
1. Wo?niak M, Go?embiowska K, Noworyta-Soko?owska K, Acher F, Cie?lik P, Kusek M, Tokarski K, Pilc A, Wiero?ska JM. Neurochemical and behavioral studies on the 5-HT(1A)-dependent antipsychotic action of the mGlu(4) receptor agonist LSP4-2022. Neuropharmacology. 2016 Jul 25. pii: S0028-3908(16)30278-7. doi: 10.1016/j.neuropharm.2016.06.025. [Epub ahead of print] PubMed PMID: 27465045.
2. Wo?niak M, Acher F, Marciniak M, Laso?-Tyburkiewicz M, Gruca P, Papp M, Pilc A, Wiero?ska JM. Involvement of GABAB Receptor Signaling in Antipsychotic-like Action of the Novel Orthosteric Agonist of the mGlu4 Receptor, LSP4-2022. Curr Neuropharmacol. 2016;14(5):413-26. PubMed PMID: 26769224; PubMed Central PMCID: PMC4983756.
3. Podkowa K, Rze?niczek S, Marciniak M, Acher F, Pilc A, Pa?ucha-Poniewiera A. A novel mGlu4 selective agonist LSP4-2022 increases behavioral despair in mouse models of antidepressant action. Neuropharmacology. 2015 Oct;97:338-45. doi: 10.1016/j.neuropharm.2015.05.039. PubMed PMID: 26074092.