LY 163443
| Code | Size | Price |
|---|
| TAR-T27877-5mg | 5mg | £930.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T27877-50mg | 50mg | £1,821.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T27877-100mg | 100mg | £2,319.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
LY 163443 is an dual receptor antagonist of LTD4 and LTE4.
CAS:
97581-70-9
Formula:
C20H22N4O3
Molecular Weight:
366.421
Purity:
0.98
SMILES:
CCCc1c(COc2ccc(Cc3nnn[nH]3)cc2)ccc(C(C)=O)c1O
References
1. Lawrence JW, Kroll DJ, Eacho PI. Ligand-dependent interaction of hepatic fatty acid-binding protein with the nucleus. J Lipid Res. 2000 Sep;41(9):1390-401. PubMed PMID: 10974046.
2. Nuessler V, Pelka-Fleischer R, Zwierzina H, Wilmanns W, Denzlinger C. Effects of progesterone and leukotriene receptor antagonists in experimental models of P-glycoprotein-related resistance. Eur J Med Res. 1997 Apr 21;2(4):159-64. PubMed PMID: 9110922.
3. Eacho PI, Foxworthy PS, Lawrence JW, Herron DK, Noonan DJ. Common structural requirements for peroxisome proliferation by tetrazole and carboxylic acid-containing compounds. Ann N Y Acad Sci. 1996 Dec 27;804:387-402. PubMed PMID: 8993558.
4. Dillard RD, Hahn RA, McCullough D, Carr FP, Rinkema LE, Roman CR, Fleisch JH. (Phenylmethoxy)phenyl derivatives of omega-oxo- and omega-tetrazolylalkanoic acids and related tetrazoles. Synthesis and evaluation as leukotriene D4 receptor antagonists. J Med Chem. 1991 Sep;34(9):2768-78. PubMed PMID: 1654427.