LY 181984
| Code | Size | Price |
|---|
| TAR-T27883-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T27883-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T27883-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
LY 181984 is an sulfonylurea with antitumor properties.
CAS:
3955-50-8
Formula:
C14H13ClN2O3S
Molecular Weight:
324.78
Purity:
0.98
SMILES:
Cc1ccc(cc1)S(=O)(=O)NC(=O)Nc1ccc(Cl)cc1
References
1. Chueh PJ, Kim C, Cho N, Morr? DM, Morr? DJ. Molecular cloning and characterization of a tumor-associated, growth-related, and time-keeping hydroquinone (NADH) oxidase (tNOX) of the HeLa cell surface. Biochemistry. 2002 Mar 19;41(11):3732-41. PubMed PMID: 11888291.
2. Morr? DJ, Chueh PJ, Lawler J, Morr? DM. The sulfonylurea-inhibited NADH oxidase activity of HeLa cell plasma membranes has properties of a protein disulfide-thiol oxidoreductase with protein disulfide-thiol interchange activity. J Bioenerg Biomembr. 1998 Oct;30(5):477-87. PubMed PMID: 9932650.
3. Morr? DJ, Wu LY, Morr? DM. Response of a cell-surface NADH oxidase to the antitumor sulfonylurea N-(4-methylphenylsulfonyl)-N'-(4-chlorophenylurea) (LY181984) modulated by redox. Biochim Biophys Acta. 1998 Mar 2;1369(2):185-92. PubMed PMID: 9518604.
4. Chern JW, Leu YL, Wang SS, Jou R, Lee CF, Tsou PC, Hsu SC, Liaw YC, Lin HM. Synthesis and cytotoxic evaluation of substituted sulfonyl-N-hydroxyguanidine derivatives as potential antitumor agents. J Med Chem. 1997 Jul 4;40(14):2276-86. PubMed PMID: 9216847.