LY 195448
| Code | Size | Price |
|---|
| TAR-T27891-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T27891-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T27891-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
LY 195448 is a phenethanolamine shown anti-tumour activity. It blocks cells at metaphase.
CAS:
111112-18-6
Formula:
C20H27ClN2O2
Molecular Weight:
362.9
Purity:
0.98
SMILES:
Cl.CC(C)(CCc1ccc(cc1)C(N)=O)NC[C@H](O)c1ccccc1
References
1. Barlow SB, Cabral F. Alterations in microtubule assembly caused by the microtubule-active drug LY195448. Cell Motil Cytoskeleton. 1991;19(1):9-17. PubMed PMID: 1863984.
2. Engineer MS, Newman RA. High-performance liquid chromatographic measurement of (R)-4-[3-[(2-hydroxy-2-phenethyl)amino]-3-methylbutyl]benzamide monohydrochloride (LY195448) and its p-hydroxy metabolite in human plasma and urine. J Chromatogr. 1990 May 18;527(2):473-80. PubMed PMID: 2387891.
3. Ho BT, Tansey LW, Engineer MS, Newman RA, Siddik ZH, Field WS, Krakoff IH. Beta-adrenoceptor binding studies with LY195448 and metabolites. Res Commun Chem Pathol Pharmacol. 1990 Jan;67(1):143-6. PubMed PMID: 2158135.
4. Ho DH, Covington WP, Lin J, Brown NS, Newman RA. Metabolism and disposition of (R)-4-[3-(2-hydroxy-2-phenyl)ethylamino-3-methylbutyl]benzamide Hcl (LY 195448) in rodents. Res Commun Chem Pathol Pharmacol. 1989 Nov;66(2):255-67. PubMed PMID: 2602657.