Lysine Orotate
| Code | Size | Price |
|---|
| TAR-T27963-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T27963-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T27963-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Lysine Orotate is an inhibitor of viral replication, especially useful to treat the Herpes family of viruses which includes Herpes Simplex 1 and 2 , CMV, EBV and Varicella.
CAS:
28003-86-3
Formula:
C11H18N4O6
Molecular Weight:
302.287
Purity:
0.98
SMILES:
NCCCC[C@H](N)C(O)=O.OC(=O)c1cc(=O)[nH]c(=O)[nH]1
References
1. Liu Y, Gao ZQ, Liu CP, Xu JH, Li LF, Ji CN, Su XD, Dong YH. Structure of the putative dihydroorotate dehydrogenase from Streptococcus mutans. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Feb 1;67(Pt 2):182-7. doi: 10.1107/S1744309110048414. Epub 2011 Jan 21. PubMed PMID: 21301083; PubMed Central PMCID: PMC3034605.
2. Wang X, Ma C, Wang X, Xu P. Orotate phosphoribosyltransferase from Corynebacterium ammoniagenes lacking a conserved lysine. J Bacteriol. 2007 Dec;189(24):9030-6. Epub 2007 Oct 5. PubMed PMID: 17921291; PubMed Central PMCID: PMC2168641.
3. Combe JP, Basran J, Hothi P, Leys D, Rigby SE, Munro AW, Scrutton NS. Lys-D48 is required for charge stabilization, rapid flavin reduction, and internal electron transfer in the catalytic cycle of dihydroorotate dehydrogenase B of Lactococcus lactis. J Biol Chem. 2006 Jun 30;281(26):17977-88. Epub 2006 Apr 19. PubMed PMID: 16624811.
4. Warshel A, Strajbl M, Vill? J, Flori?n J. Remarkable rate enhancement of orotidine 5'-monophosphate decarboxylase is due to transition-state stabilization rather than to ground-state destabilization. Biochemistry. 2000 Dec 5;39(48):14728-38. PubMed PMID: 11101287.