mCPBG
| Code | Size | Price |
|---|
| TAR-T27987-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T27987-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T27987-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
mCPBG is a potent high affinity agonist of 5-HT3 receptor.
CAS:
48144-44-1
Formula:
C8H10ClN5
Molecular Weight:
211.65
Purity:
0.98
SMILES:
NC(N)=NC(=N)Nc1cccc(Cl)c1
References
1. Dale E, Grunnet M, Pehrson AL, Frederiksen K, Larsen PH, Nielsen J, Stensb?l TB, Ebert B, Yin H, Lu D, Liu H, Jensen TN, Yang CR, Sanchez C. The multimodal antidepressant vortioxetine may facilitate pyramidal cell firing by inhibition of 5-HT(3) receptor expressing interneurons: An in vitro study in rat hippocampus slices. Brain Res. 2017 Dec 21. pii: S0006-8993(17)30559-0. doi: 10.1016/j.brainres.2017.12.025. [Epub ahead of print] PubMed PMID: 29274875.
2. Amiri Gheshlaghi S, Mohammad Jafari R, Algazo M, Rahimi N, Alshaib H, Dehpour AR. Genistein modulation of seizure: involvement of estrogen and serotonin receptors. J Nat Med. 2017 Jul;71(3):537-544. doi: 10.1007/s11418-017-1088-3. Epub 2017 Apr 24. PubMed PMID: 28439683.
3. Price KL, Hirayama Y, Lummis SCR. Subtle Differences among 5-HT(3)AC, 5-HT(3)AD, and 5-HT(3)AE Receptors Are Revealed by Partial Agonists. ACS Chem Neurosci. 2017 May 17;8(5):1085-1091. doi: 10.1021/acschemneuro.6b00416. Epub 2017 Apr 3. PubMed PMID: 28367632.
4. Pratt WE, Lin P, Pierce-Messick Z, Ilesanmi AO, Clissold KA. Contrasting effects of 5-HT(3) receptor stimulation of the nucleus accumbens or ventral tegmentum on food intake in the rat. Behav Brain Res. 2017 Apr 14;323:15-23. doi: 10.1016/j.bbr.2017.01.031. Epub 2017 Jan 20. PubMed PMID: 28115218; PubMed Central PMCID: PMC5333165.