MDK0734
| Code | Size | Price |
|---|
| TAR-T27989-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T27989-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T27989-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
MDK0734 is a selective inhibitor of cathepsin B endopeptidase and exopeptidase activities.
CAS:
1366240-73-4
Formula:
C15H17N3O2
Molecular Weight:
271.32
Purity:
0.98
SMILES:
CC1CCN(CC1)c1ccc([N+]([O-])=O)c2cccnc12
References
1. Chen H, Lv M, Lv Z, Li C, Zhang W, Zhao X, Duan X, Jin C, Xiong J, Xu F, Li Y. Divergent roles of three cytochrome c in CTSB-modulating coelomocyte apoptosis in Apostichopus japonicus. Dev Comp Immunol. 2017 May 24;76:65-76. doi: 10.1016/j.dci.2017.05.018. [Epub ahead of print] PubMed PMID: 28549733.
2. Li H, Wang F, Ge S, Liu H, Yan M, Yu J. Turning Nonspecific Interference into Signal Amplification: Covalent Biosensing Nanoassembly Enabled by Metal-Catalyzed Cross-Coupling. Anal Chem. 2017 May 26. doi: 10.1021/acs.analchem.7b01269. [Epub ahead of print] PubMed PMID: 28548821.
3. Xie X, Yi W, Zhang P, Wu N, Yan Q, Yang H, Tian C, Xiang S, Du M, Getachew Assefa E, Zuo X, Ying C. Green Tea Polyphenols, Mimicking the Effects of Dietary Restriction, Ameliorate High-Fat Diet-Induced Kidney Injury via Regulating Autophagy Flux. Nutrients. 2017 May 14;9(5). pii: E497. doi: 10.3390/nu9050497. PubMed PMID: 28505110.
4. Zhang X, Yang X, Wang H, Li S, Guo K, Jiang D, Xiao J, Liang D. Design, synthesis, and structure-activity relationship study of epoxysuccinyl-peptide derivatives as cathepsin B inhibitors. Biol Pharm Bull. 2017 May 13. doi: 10.1248/bpb.b17-00075. [Epub ahead of print] PubMed PMID: 28502922.