mPGES-1 Inhibitor-1
Code | Size | Price |
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TAR-T28089-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T28089-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T28089-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
mPGES-1 Inhibitor-1 is a novel selective inhibitor of microsomal prostaglandin E synthase-1 (mPGES-1) .
CAS:
1381846-21-4
Formula:
C16H19ClN4O2
Molecular Weight:
334.8
Purity:
0.98
SMILES:
CC(C)(C)C(=O)NCc1ccc(Cl)c(c1)C(=O)Nc1ncc[nH]1
References
1. Avenda?o MS, Mart?nez-Revelles S, Aguado A, Sim?es MR, Gonz?lez-Amor M, Palacios R, Guillem-Llobat P, Vassallo DV, Vila L, Garc?a-Puig J, Beltr?n LM, Alonso MJ, Cachofeiro MV, Salaices M, Briones AM. Role of COX-2-derived PGE2 on vascular stiffness and function in hypertension. Br J Pharmacol. 2016 May;173(9):1541-55. doi: 10.1111/bph.13457. Epub 2016 Mar 21. PubMed PMID: 26856544; PubMed Central PMCID: PMC4831311.
2. Bylund J, Bueters T. Presystemic metabolism of AZ'0908, a novel mPGES-1 inhibitor: an in vitro and in vivo cross-species comparison. J Pharm Sci. 2013 Mar;102(3):1106-15. doi: 10.1002/jps.23443. Epub 2013 Jan 11. PubMed PMID: 23316000.