MTC420
Code | Size | Price |
---|
TAR-T28120-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T28120-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T28120-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
MTC420 is a anti-tuberculosis agent with acceptable anti-tuberculosis activity (Mtb IC50 =525 nM, Mtb Wayne IC50 = 76 nM and MDR Mtb patient isolates IC50 = 140 nM).
CAS:
2088930-66-7
Formula:
C20H16F4N2O
Molecular Weight:
376.355
Purity:
0.98
SMILES:
Cc1c([nH]c2cc(F)cc(F)c2c1=O)-c1ccc(cc1)N1CCC(F)(F)C1
References
1. Hong WD, Gibbons PD, Leung SC, Amewu R, Stocks PA, Stachulski AV, Horta PC, Cristiano ML, Shone AE, Moss D, Ardrey A, Sharma R, Warman AJ, Bedingfield PT, Fisher NE, Aljayyoussi G, Mead S, Caws M, Berry NG, Ward SA, Biagini GA, O'Neill PM, Nixon GL. Rational Design, Synthesis and Biological Evaluation of Heterocyclic Quinolones Targeting the respiratory chain of Mycobacterium tuberculosis. J Med Chem. 2017 Mar 17. doi: 10.1021/acs.jmedchem.6b01718. [Epub ahead of print] PubMed PMID: 28304162.