NDM-1 inhibitor-2

TargetMol
Product Code: TAR-T28149
Supplier: TargetMol
CodeSizePrice
TAR-T28149-5mg5mg£850.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T28149-50mg50mg£1,661.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T28149-100mg100mg£2,079.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

1 / 1

Further Information

Bioactivity:
NDM-1 inhibitor-2 is an inhibitor of new delhi metallo-β-lactamase-1 (NDM-1).
CAS:
665013-76-3
Formula:
C9H9BrN4S
Molecular Weight:
285.16
Purity:
0.98
SMILES:
Sc1nncn1NCc1cccc(Br)c1

References

1. Chen AY, Thomas PW, Stewart AC, Bergstrom A, Cheng Z, Miller C, Bethel CR, Marshall SH, Credille CV, Riley CL, Page RC, Bonomo RA, Crowder MW, Tierney DL, Fast W, Cohen SM. Dipicolinic Acid Derivatives as Inhibitors of New Delhi Metallo-?-lactamase-1. J Med Chem. 2017 Sep 14;60(17):7267-7283. doi: 10.1021/acs.jmedchem.7b00407. Epub 2017 Aug 30. PubMed PMID: 28809565; PubMed Central PMCID: PMC5599375. 2. Shen B, Zhu C, Gao X, Liu G, Song J, Yu Y. Oligopeptides as full-length New Delhi metallo-?-lactamase-1 (NDM-1) inhibitors. PLoS One. 2017 May 23;12(5):e0177293. doi: 10.1371/journal.pone.0177293. eCollection 2017. PubMed PMID: 28542279; PubMed Central PMCID: PMC5441612. 3. Ul Haq F, Abro A, Raza S, Liedl KR, Azam SS. Molecular dynamics simulation studies of novel ?-lactamase inhibitor. J Mol Graph Model. 2017 Jun;74:143-152. doi: 10.1016/j.jmgm.2017.03.002. Epub 2017 Apr 4. PubMed PMID: 28432959. 4. Groundwater PW, Xu S, Lai F, V?radi L, Tan J, Perry JD, Hibbs DE. New Delhi metallo-?-lactamase-1: structure, inhibitors and detection of producers. Future Med Chem. 2016 Jun;8(9):993-1012. doi: 10.4155/fmc-2016-0015. Epub 2016 Jun 2. Review. PubMed PMID: 27253479.