OP-2507
| Code | Size | Price |
|---|
| TAR-T28254-5mg | 5mg | £1,492.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T28254-50mg | 50mg | £2,946.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T28254-100mg | 100mg | £4,006.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
OP-2507, a prostacyclin agonist, is used potentially for the treatment of hepatic insufficiency and hypertension.
CAS:
101758-79-6
Formula:
C25H41NO4
Molecular Weight:
419.606
Purity:
0.98
SMILES:
[H][C@]12C[C@@H](O)[C@H](C=C[C@@H](O)C3CCC(CCC)CC3)[C@@]1([H])CC(CCCCC(=O)OC)=N2
References
1. Usui M, Kato H, Kuriyama N, Azumi Y, Kishiwada M, Mizuno S, Sakurai H, Tabata M, Hayashi T, Suzuki K, Isaji S. Effect of a prostaglandin I(2) analog on the expression of thrombomodulin in liver and spleen endothelial cells after an extensive hepatectomy. Surg Today. 2011 Feb;41(2):230-6. doi: 10.1007/s00595-009-4263-7. PubMed PMID: 21264759.
2. Kurata M, Okajima K, Kawamoto T, Uchiba M, Ohkohchi N. Antithrombin reduces reperfusion-induced hepatic metastasis of colon cancer cells. World J Gastroenterol. 2006 Jan 7;12(1):60-5. PubMed PMID: 16440418; PubMed Central PMCID: PMC4077492.
3. Chen MF, Chen JC, Chiu DF, Ng CJ, Shyr MH, Chen HM. Prostacyclin analogue (OP-2507) induces delayed ex vivo neutrophil apoptosis and attenuates reperfusion-induced hepatic microcirculatory derangement in rats. Shock. 2001 Dec;16(6):473-8. PubMed PMID: 11770047.
4. Hirano T, Nakafusa Y, Kawano R, Motoyama K, Arima T, Sugitani A, Tanaka M. The combined use of prostaglandin I2 analogue (OP-2507) and thromboxane A2 synthetase inhibitor (OKY-046) strongly inhibits atherosclerosis of aortic allografts in rats. Surgery. 2001 May;129(5):595-605. PubMed PMID: 11331452.