Org-21465
Code | Size | Price |
---|
TAR-T28259-5mg | 5mg | £1,091.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T28259-50mg | 50mg | £2,143.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T28259-100mg | 100mg | £2,801.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
Org-21465, a gamma-aminobutyric acid (GABA) receptor agonist, is used potentially for the use of anesthesia.
CAS:
167946-96-5
Formula:
C27H43NO4
Molecular Weight:
445.644
Purity:
0.98
SMILES:
[H][C@@]12CC[C@H](C(C)=O)[C@@]1(C)CC(=O)[C@@]1([H])[C@@]2([H])CC[C@@]2([H])C[C@H](O)[C@H](C[C@]12C)N1CCOC(C)(C)C1
References
1. Vanlersberghe C, Camu F. Etomidate and other non-barbiturates. Handb Exp Pharmacol. 2008;(182):267-82. doi: 10.1007/978-3-540-74806-9_13. Review. PubMed PMID: 18175096.
2. Visser SA, Gladdines WW, van der Graaf PH, Peletier LA, Danhof M. Neuroactive steroids differ in potency but not in intrinsic efficacy at the GABA(A) receptor in vivo. J Pharmacol Exp Ther. 2002 Nov;303(2):616-26. PubMed PMID: 12388643.
3. Manuel NA, Davies CH. Pharmacological modulation of GABA(A) receptor-mediated postsynaptic potentials in the CA1 region of the rat hippocampus. Br J Pharmacol. 1998 Dec;125(7):1529-42. PubMed PMID: 9884082; PubMed Central PMCID: PMC1565743.
4. Sneyd JR, Wright PM, Harris D, Taylor PA, Vijn PC, Cross M, Dale H, Voortman G, Boen P. Computer-controlled infusion of ORG 21465, a water soluble steroid i.v. anaesthetic agent, into human volunteers. Br J Anaesth. 1997 Oct;79(4):433-9. Erratum in: Br J Anaesth 2001 Feb;86(2):302. PubMed PMID: 9389258.