Org-31710
| Code | Size | Price |
|---|
| TAR-T28263-5mg | 5mg | £1,653.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T28263-50mg | 50mg | £3,267.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T28263-100mg | 100mg | £4,488.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Org-31710 is a progesterone receptor antagonist potentially for contraception.
CAS:
118968-41-5
Formula:
C30H39NO2
Molecular Weight:
445.647
Purity:
0.98
SMILES:
[H][C@@]12CC[C@@]3(CCCO3)[C@@]1(C)C[C@@H](C1=C3CCC(=O)C=C3[C@H](C)C[C@@]21[H])c1ccc(cc1)N(C)C
References
1. Goyeneche AA, Seidel EE, Telleria CM. Growth inhibition induced by antiprogestins RU-38486, ORG-31710, and CDB-2914 in ovarian cancer cells involves inhibition of cyclin dependent kinase 2. Invest New Drugs. 2012 Jun;30(3):967-80. doi: 10.1007/s10637-011-9655-z. PubMed PMID: 21424700; PubMed Central PMCID: PMC3348464.
2. Petersen A, Bentin-Ley U, Ravn V, Qvortrup K, S?rensen S, Islin H, Sj?gren A, Mosselmann S, Hamberger L. The antiprogesterone Org 31710 inhibits human blastocyst-endometrial interactions in vitro. Fertil Steril. 2005 Apr;83 Suppl 1:1255-63. PubMed PMID: 15831300.
3. Mulders TM, Mink CP, Bobbink IW, Bennink HJ. Safety, tolerability, and pharmacokinetics of a novel, selective antiprogestagen (Org 31710) in healthy male volunteers. Contraception. 1998 Jul;58(1):39-44. PubMed PMID: 9743895.
4. van Heusden AM, Killick SR, Coelingh Bennink HJ, Fauser BC. Single monthly administration of the anti-progestagen Org 31710 in users of the 75 microg desogestrel progestagen-only pill: effects on pituitary-ovarian activity. Hum Reprod. 2000 Mar;15(3):629-36. PubMed PMID: 10686210.