Osemozotan HCl
Code | Size | Price |
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TAR-T28270-5mg | 5mg | £1,010.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T28270-50mg | 50mg | £1,982.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T28270-100mg | 100mg | £2,560.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
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Further Information
Bioactivity:
Osemozotan is a 5-HT1A receptor agonist potentially for the treatment of generalized anxiety disorder.
CAS:
137275-80-0
Formula:
C19H22ClNO5
Molecular Weight:
379.84
Purity:
0.98
SMILES:
Cl.C(CNC[C@H]1COc2ccccc2O1)COc1ccc2OCOc2c1
References
1. Matsuda T. Neuropharmacologic studies on the brain serotonin1A receptor using the selective agonist osemozotan. Biol Pharm Bull. 2013;36(12):1871-82. Review. PubMed PMID: 24292048.
2. Tsuchida R, Kubo M, Shintani N, Abe M, K?ves K, Uetsuki K, Kuroda M, Hashimoto H, Baba A. Inhibitory effects of osemozotan, a serotonin 1A-receptor agonist, on methamphetamine-induced c-Fos expression in prefrontal cortical neurons. Biol Pharm Bull. 2009 Apr;32(4):728-31. PubMed PMID: 19336914.
3. Tsuchida R, Kubo M, Kuroda M, Shibasaki Y, Shintani N, Abe M, K?ves K, Hashimoto H, Baba A. An antihyperkinetic action by the serotonin 1A-receptor agonist osemozotan co-administered with psychostimulants or the non-stimulant atomoxetine in mice. J Pharmacol Sci. 2009 Mar;109(3):396-402. Epub 2009 Mar 7. PubMed PMID: 19270432.
4. Ago Y, Nakamura S, Hayashi A, Itoh S, Baba A, Matsuda T. Effects of osemozotan, ritanserin and azasetron on cocaine-induced behavioral sensitization in mice. Pharmacol Biochem Behav. 2006 Sep;85(1):198-205. Epub 2006 Sep 8. PubMed PMID: 16962650.