Oxendolone
| Code | Size | Price |
|---|
| TAR-T28280-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Oxendolone is a steroidal progestin and antiandrogen. Oxendolone binds to the progesterone receptor (Ki = 20 nM) and androgen receptor (AR) (Ki = 320 nM) and acts as a weak but clinically relevant inhibitor of 5α-reductase.
CAS:
33765-68-3
Formula:
C20H30O2
Molecular Weight:
302.458
Purity:
0.98
SMILES:
CC[C@H]1C[C@H]2[C@@H]3CCC4=CC(=O)CC[C@@H]4[C@H]3CC[C@]2(C)[C@H]1O
References
1. Hikichi Y, Yamaoka M, Kusaka M, Hara T. Selective androgen receptor modulator activity of a steroidal antiandrogen TSAA-291 and its cofactor recruitment profile. Eur J Pharmacol. 2015 Oct 15;765:322-31. doi: 10.1016/j.ejphar.2015.08.052. Epub 2015 Sep 1. PubMed PMID: 26335395.
2. Matsuda H, Yamazaki M, Naruo S, Asanuma Y, Kubo M. Anti-androgenic and hair growth promoting activities of Lygodii spora (spore of Lygodium japonicum) I. Active constituents inhibiting testosterone 5alpha-reductase. Biol Pharm Bull. 2002 May;25(5):622-6. PubMed PMID: 12033503.
3. Yamada K, Komatsu H, Ohta A. Effects of 3,6-dimethylpyrazine-2-thiol on reproductive and accessory reproductive organs in male rats. Biol Pharm Bull. 1996 Mar;19(3):360-3. PubMed PMID: 8924900.
4. Iguchi H, Ikeuchi T, Kai Y, Yoshida H. [Influence of anti-androgen therapy for prostatic hypertrophy on lipid metabolism]. Hinyokika Kiyo. 1994 Mar;40(3):215-9. Japanese. PubMed PMID: 7513937.