PF-02367982
| Code | Size | Price |
|---|
| TAR-T28361-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
PF-02367982 is a potent, selective nonsteroidal progesterone antagonist.
CAS:
913344-84-0
Formula:
C19H20N4O2
Molecular Weight:
336.395
Purity:
0.98
SMILES:
CNC(=O)Cn1nc(C2CC2)c(Oc2ccc(cc2)C#N)c1C1CC1
References
1. Schmidt C, Klammt J, Thome UH, Laube M. The interaction of glucocorticoids and progesterone distinctively affects epithelial sodium transport. Lung. 2014 Dec;192(6):935-46. doi: 10.1007/s00408-014-9640-3. Epub 2014 Aug 31. PubMed PMID: 25173779.
2. de Giorgio-Miller A, Bungay P, Tutt M, Owen J, Goodwin D, Pullen N. The translational pharmacology of a novel, potent, and selective nonsteroidal progesterone receptor antagonist, 2-[4-(4-cyano-phenoxy)-3,5-dicyclopropyl-1H-pyrazol-1-yl]-N-methylacetamide (PF-02367982). J Pharmacol Exp Ther. 2008 Oct;327(1):78-87. doi: 10.1124/jpet.108.140467. Epub 2008 Jul 1. PubMed PMID: 18593954.