PF-462991
Code | Size | Price |
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TAR-T28385-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T28385-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T28385-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
PF-462991 is a S1P1 agonist.
CAS:
1149727-90-1
Formula:
C25H29N3O3
Molecular Weight:
419.525
Purity:
0.98
SMILES:
CC(C)Cc1ccc(cc1)-c1nc(no1)-c1ccc(cc1)[C@@H](C)N[C@H]1C[C@H](C1)C(O)=O
References
1. Stabilization of alcohol intoxication-?induced cardiovascular instability using sphingosine-?1-?phosphate (S1P) receptor modulators By Breslin, Jerome William; Doggett, Travis Matthew From U.S. Pat. Appl. Publ. (2017), US 20170020826 A1 20170126. | Language: English, Database: CAPLUS
2. No differences observed among multiple clinical S1P1 receptor agonists (functional antagonists) in S1P1 receptor down-?regulation and degradation By Lukas, Susan; Patnaude, Lori; Haxhinasto, Sokol; Slavin, Anthony; Hill-Drzewi, Melissa; Horan, Josh; Modis, Louise Kelly From Journal of Biomolecular Screening (2014), 19(3), 407-416, 10. | Language: English, Database: CAPLUS
3. Identification of benzoxazole analogs as novel, S1P3 sparing S1P1 agonists By Deng, Guanghui; Meng, Qinghua; Liu, Qian; Xu, Xuesong; Xu, Qiongfeng; Ren, Feng; Guo, Taylor B.; Lu, Hongtao; Xiang, Jia-Ning; Elliott, John D.; et al. From Bioorganic & Medicinal Chemistry Letters (2012), 22(12), 3973-3977. | Language: English, Database: CAPLUS
4. Methods of treating pain by administering an agent that suppresses sphingosine-?1-?phosphate biologcial activity By Salvemini, Daniela. From PCT Int. Appl. (2012), WO 2012015758 A2 20120202. | Language: English, Database: CAPLUS