Pirlindole free base

TargetMol
Product Code: TAR-T28422
Supplier: TargetMol
CodeSizePrice
TAR-T28422-50mg50mg£752.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T28422-100mg100mg£1,099.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
Pirlindole is a reversible inhibitor of monoamine oxidase A (RIMA). It is structurally and pharmacologically related to metralindole.
CAS:
60762-57-4
Formula:
C15H18N2
Molecular Weight:
226.32
Purity:
0.98
SMILES:
CC1=CC2=C(C=C1)N3C4=C2CCCC4NCC3

References

1. Macedo A, Leiria E, Filipe A. Pirlindole in the treatment of depression: a meta-analysis. Clin Drug Investig. 2011;31(1):61-71. doi: 10.2165/11586690-000000000-00000. PubMed PMID: 21053988. 2. Branco JC, Tom? AM, Cruz MR, Filipe A. Pirlindole in the treatment of depression and fibromyalgia syndrome. Clin Drug Investig. 2011 Oct 1;31(10):675-89. doi: 10.2165/11595410-000000000-00000. Review. PubMed PMID: 21877764. 3. Fiedler VB, Buchheim S, Nitz RE, Scholtholt J. Haemodynamic effects of pirlindole, a new tetracyclic antidepressant agent. Arzneimittelforschung. 1983;33(2):244-50. PubMed PMID: 6682664. 4. Boland A, G?rardy J, Mossay D, Seutin V. Pre- and post-treatment with pirlindole and dehydropirlindole protects cultured brain cells against nitric oxide-induced death. Eur J Pharmacol. 2003 Apr 11;466(1-2):21-30. PubMed PMID: 12679138.