PP30

TargetMol
Product Code: TAR-T28439
Supplier: TargetMol
CodeSizePrice
TAR-T28439-5mg5mg£850.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T28439-50mg50mg£1,661.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T28439-100mg100mg£2,079.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
PP30 is an inhibitor of mTORC1 and mTORC2. It is selective within the PI3K family, inhibiting other PI3Ks only at high concentrations.
CAS:
1092788-09-4
Formula:
C18H19N7OS
Molecular Weight:
381.46
Purity:
0.98
SMILES:
CC(C)n1nc(-c2cccc(c2)C(=O)NC2=NCCS2)c2c(N)ncnc12

References

1. Yang K, Jin Y, Xing C, Hu J, Wang R, Sun P. Chemical Characterization and In Vitro Antioxidant Activity Evaluation of Polysaccharides from the Fruiting Bodies of the Red Heart Mushroom Phellinus pini (Higher Basidiomycetes). Int J Med Mushrooms. 2015;17(3):297-307. PubMed PMID: 25954913. 2. Wang L, Li Z, He C. Transcriptome-wide mining of the differentially expressed transcripts for natural variation of floral organ size in Physalis philadelphica. J Exp Bot. 2012 Nov;63(18):6457-65. doi: 10.1093/jxb/ers299. Epub 2012 Oct 17. PubMed PMID: 23081983; PubMed Central PMCID: PMC3504495. 3. Shen X, Ye G, Cheng X, Yu C, Altosaar I, Hu C. Characterization of an abaecin-like antimicrobial peptide identified from a Pteromalus puparum cDNA clone. J Invertebr Pathol. 2010 Sep;105(1):24-9. doi: 10.1016/j.jip.2010.05.006. Epub 2010 May 11. PubMed PMID: 20466006. 4. Feldman ME, Apsel B, Uotila A, Loewith R, Knight ZA, Ruggero D, Shokat KM. Active-site inhibitors of mTOR target rapamycin-resistant outputs of mTORC1 and mTORC2. PLoS Biol. 2009 Feb 10;7(2):e38. doi: 10.1371/journal.pbio.1000038. PubMed PMID: 19209957; PubMed Central PMCID: PMC2637922.