PPQ-581

TargetMol
Product Code: TAR-T28443
Supplier: TargetMol
CodeSizePrice
TAR-T28443-5mg5mg£850.00
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Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
PPQ-581 is an anti-influenza agent. PPQ-581 interrupts the crucial RNP trafficking, resulting in influenza replication inhibition, preventing virus-induced cytopathic effects.
CAS:
950381-32-5
Formula:
C25H24FN3O3
Molecular Weight:
433.483
Purity:
0.98
SMILES:
Cn1c2c3C(OCC(C)(C)n3c(-c3ccccc3)c2c(=O)n(C)c1=O)c1ccccc1F

References

1. Lin MI, Su BH, Lee CH, Wang ST, Wu WC, Dangate P, Wang SY, Huang WI, Cheng TJ, Lin OA, Cheng YS, Tseng YJ, Sun CM. Synthesis and inhibitory effects of novel pyrimido-pyrrolo-quinoxalinedione analogues targeting nucleoproteins of influenza A virus H1N1. Eur J Med Chem. 2015 Sep 18;102:477-86. doi: 10.1016/j.ejmech.2015.08.016. Epub 2015 Aug 13. PubMed PMID: 26310893.