TargetMol

Imperatorin

Product Code:
 
TAR-T2845
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T2845-25mg25mg£103.00
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Quantity:
TAR-T2845-1mL1 mL * 10 mM (in DMSO)£107.00
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TAR-T2845-50mg50mg£124.00
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TAR-T2845-100mg100mg£148.00
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This product comes from: United States.
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Further Information

Bioactivity:
Imperatorin is a modulator of p38, ERK pathway. Imperatorin increases BMP-2 expression (mRNA) and increases bone density/volume and mineralization in vivo.
CAS:
482-44-0
Formula:
C16H14O4
Molecular Weight:
270.284
Pathway:
NF-κb; Membrane transporter/Ion channel; Neuroscience; Immunology/Inflammation
Purity:
0.9807
SMILES:
CC(C)=CCOc1c2occc2cc2ccc(=O)oc12
Target:
TRP/TRPV Channel; AChR; AChE; NOD

References

1. Kozio?, E., & Skalicka-Wo?niak, K. (2016). Imperatorin?pharmacological meaning and analytical clues: profound investigation.?Phytochemistry Reviews,?15(4), 627-649. doi: 10.1007/s11101-016-9456-2 2. Chen X, et al. Furanocoumarins are a novel class of modulators for the transient receptor potential vanilloid type 1 (TRPV1) channel. J Biol Chem. 2014 Apr 4;289(14):9600-10. 3. Budzynska B, et al. Effects of imperatorin on scopolamine-induced cognitive impairment and oxidative stress in mice. Psychopharmacology (Berl). 2015 Mar;232(5):931-42.