Q8 hydrochloride

TargetMol
Product Code: TAR-T28481
Supplier: TargetMol
CodeSizePrice
TAR-T28481-5mg5mg£850.00
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Quantity:
TAR-T28481-50mg50mg£1,661.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T28481-100mg100mg£2,079.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
Q8 is an antagonist of cysteinyl leukotreine receptor. Q8 inhibits VEGF-independent angiogenesis.
CAS:
1541762-55-3
Formula:
C17H14ClNO2
Molecular Weight:
299.75
Purity:
0.98
SMILES:
Cl.Oc1ccc(O)c(C=Cc2ccc3ccccc3n2)c1

References

1. Dugel PU, Jaffe GJ, Sallstig P, Warburton J, Weichselberger A, Wieland M, Singerman L. Brolucizumab Versus Aflibercept in Participants with Neovascular Age-Related Macular Degeneration: A Randomized Trial. Ophthalmology. 2017 May 24. pii: S0161-6420(16)32413-7. doi: 10.1016/j.ophtha.2017.03.057. [Epub ahead of print] PubMed PMID: 28551167. 2. Choi SK, Schurig-Briccio L, Ding Z, Hong S, Sun C, Gennis RB. Location of the substrate binding site of the cytochrome bo(3) ubiquinol oxidase from Escherichia coli. J Am Chem Soc. 2017 May 24. doi: 10.1021/jacs.7b03883. [Epub ahead of print] PubMed PMID: 28538096. 3. de Vink P, Briels J, Schrader T, Milroy L, Brunsveld L, Ottmann C. Cucurbit[8]uril and 14-3-3 based binary bivalent supramolecular-protein assembly platform and co-crystal structure. Angew Chem Int Ed Engl. 2017 May 16. doi: 10.1002/anie.201701807. [Epub ahead of print] PubMed PMID: 28510303. 4. Zhao M, Lepak AJ, Marchillo K, VanHecker J, Andes DR. In Vivo Pharmacodynamic Target Assessment of Eravacycline against Escherichia Coli in a Murine Thigh Infection Model. Antimicrob Agents Chemother. 2017 Apr 17. pii: AAC.00250-17. doi: 10.1128/AAC.00250-17. [Epub ahead of print] PubMed PMID: 28416552.