Renzapride hydrochloride
| Code | Size | Price |
|---|
| TAR-T28517-5mg | 5mg | £930.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T28517-50mg | 50mg | £1,821.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T28517-100mg | 100mg | £2,319.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Renzapride is a 5-HT3 antagonist and 5-HT4 agonist. Renzapride also functions as a 5-HT2B antagonist and has some affinity for the 5-HT2A and 5-HT2C receptors.
CAS:
109872-41-5
Formula:
C16H23Cl2N3O2
Molecular Weight:
360.28
Purity:
0.98
SMILES:
Cl.[H][C@]12CCCN(CC[C@@H]1NC(=O)c1cc(Cl)c(N)cc1OC)C2
References
1. Mozaffari S, Nikfar S, Abdollahi M. Efficacy and tolerability of renzapride in irritable bowel syndrome: a meta-analysis of randomized, controlled clinical trials including 2528 patients. Arch Med Sci. 2014 Feb 24;10(1):10-8. doi: 10.5114/aoms.2014.40729. Epub 2014 Feb 23. Review. PubMed PMID: 24701208; PubMed Central PMCID: PMC3953973.
2. Ford AC. Renzapride in IBS: is efficacy in the eye of the beholder? Aliment Pharmacol Ther. 2010 Jul;32(1):113-4; author reply 114-5. doi: 10.1111/j.1365-2036.2010.04275.x. PubMed PMID: 20597877.
3. Lembo AJ, Cremonini F, Meyers N, Hickling R. Clinical trial: renzapride treatment of women with irritable bowel syndrome and constipation - a double-blind, randomized, placebo-controlled, study. Aliment Pharmacol Ther. 2010 May;31(9):979-90. doi: 10.1111/j.1365-2036.2010.04265.x. Epub 2010 Feb 16. PubMed PMID: 20163375.
4. Scarpellini E, Tack J. Renzapride: a new drug for the treatment of constipation in the irritable bowel syndrome. Expert Opin Investig Drugs. 2008 Nov;17(11):1663-70. doi: 10.1517/13543784.17.11.1663 . Review. PubMed PMID: 18922103.