Ro 12-7310
| Code | Size | Price |
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| TAR-T28554-5mg | 5mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Quantity:
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Ro 12-7310, a synthetic retinoid, inhibits arachidonic acid release.
CAS:
65316-65-6
Formula:
C20H24O3
Molecular Weight:
312.409
Purity:
0.98
SMILES:
CC(C=Cc1c(C)cc(O)c(C)c1C)=C/C=C/C(/C)=C/C(O)=O
References
1. Chaudhuri BN, Kleywegt GJ, Broutin-L'Hermite I, Bergfors T, Senn H, Le Motte P, Partouche O, Jones TA. Structures of cellular retinoic acid binding proteins I and II in complex with synthetic retinoids. Acta Crystallogr D Biol Crystallogr. 1999 Nov;55(Pt 11):1850-7. PubMed PMID: 10531482.
2. Wyss R, Bucheli F, Hartenbach R. Determination of 13-cis-3-hydroxyretinoic acid, all-trans-3-hydroxyretinoic acid and their 4-oxo metabolites in human and animal plasma by high-performance liquid chromatography with automated column switching and UV detection. J Pharm Biomed Anal. 1998 Dec;18(4-5):761-76. PubMed PMID: 9919979.
3. elAttar TM, Lin HS. In vitro inhibition of prostaglandin biosynthesis in squamous cell carcinoma by retinoids. Eicosanoids. 1990;3(2):95-8. PubMed PMID: 2144980.
4. Fiedler-Nagy C, Wittreich BH, Georgiadis A, Hope WC, Welton AF, Coffey JW. Comparative study of natural and synthetic retinoids as inhibitors of arachidonic acid release and metabolism in rat peritoneal macrophages. Dermatologica. 1987;175 Suppl 1:81-92. PubMed PMID: 2826266.