Ro 14-7437
Code | Size | Price |
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TAR-T28556-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T28556-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T28556-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
Ro 14-7437 is an antagonist of GABA-benzodiazepine receptor.
CAS:
78756-03-3
Formula:
C15H15N3O3
Molecular Weight:
285.303
Purity:
0.98
SMILES:
CCOC(=O)c1ncn-2c1CN(C)C(=O)c1ccccc-21
References
1. Harris BD, Moody EJ, Gu ZQ, Skolnick P. Contribution of "diazepam-insensitive" GABAA receptors to the alcohol antagonist properties of Ro 15-4513 and related imidazobenzodiazepines. Pharmacol Biochem Behav. 1995 Sep;52(1):113-8. PubMed PMID: 7501652.
2. P?sp?k A, Herneth A, Steindl P, Ferenci P. Hepatic encephalopathy in rats with thioacetamide-induced acute liver failure is not mediated by endogenous benzodiazepines. Gastroenterology. 1993 Sep;105(3):851-7. PubMed PMID: 8359654.
3. Basile AS, Gammal SH, Mullen KD, Jones EA, Skolnick P. Differential responsiveness of cerebellar Purkinje neurons to GABA and benzodiazepine receptor ligands in an animal model of hepatic encephalopathy. J Neurosci. 1988 Jul;8(7):2414-21. PubMed PMID: 2854841.
4. Laurent JP. [Pharmacologic bases of the action of benzodiazepine ligands]. Rev Med Suisse Romande. 1987 Sep;107(9):711-5. Review. French. PubMed PMID: 2827289.