Ro 15-3505
Code | Size | Price |
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TAR-T28558-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T28558-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T28558-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
Ro 15-3505, a benzodiazepine receptor partial inverse agonist, has shown the ability to improve impaired recent memory of aged mice.
CAS:
78756-33-9
Formula:
C15H14ClN3O3
Molecular Weight:
319.75
Purity:
0.98
SMILES:
CCOC(=O)c1ncn-2c1CN(C)C(=O)c1cc(Cl)ccc-21
References
1. Forster MJ, Prather PL, Patel SR, Lal H. The benzodiazepine receptor inverse agonist RO 15-3505 reverses recent memory deficits in aged mice. Pharmacol Biochem Behav. 1995 Jun-Jul;51(2-3):557-60. PubMed PMID: 7667387.
2. Najim RA, Karim KH. Prevention of ethanol-induced gastric damage by the imidazobenzodiazepines Ro 15-4513 and Ro 15-3505 in rats. Pharmacol Biochem Behav. 1993 Jul;45(3):597-9. PubMed PMID: 8332622.
3. Bianchi M, Mantegazza P, Tammiso R, Zonta N, Zambotti F. Peripherally administered benzodiazepines increase morphine-induced analgesia in the rat. Effect of RO 15-3505 and FG 7142. Arch Int Pharmacodyn Ther. 1993 Mar-Apr;322:5-13. PubMed PMID: 8215717.
4. Gentil V, Tavares S, Gorenstein C, Bello C, Mathias L, Gronich G, Singer J. Acute reversal of flunitrazepam effects by Ro 15-1788 and Ro 15-3505: inverse agonism, tolerance, and rebound. Psychopharmacology (Berl). 1990;100(1):54-9. PubMed PMID: 2104987.