Ro 16-6491
Code | Size | Price |
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TAR-T28559-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T28559-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T28559-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
Ro 16-6491 is a selective, reversible, orally-active inhibitor of MAO-B.
CAS:
87235-61-8
Formula:
C9H11ClN2O
Molecular Weight:
198.65
Purity:
0.98
SMILES:
NCCNC(=O)c1ccc(Cl)cc1
References
1. DeJesus OT, Flores LG, Roberts AD, Dick DW, Bartlett RM, Murali D, Nickles RJ. Aromatic L-amino acid decarboxylase (AAAD) activity in rhesus macaque striatum after MAO-B inhibition by Ro 16-6491. Synapse. 2005 Apr;56(1):54-6. PubMed PMID: 15700282.
2. Mullan EL, Williams CH. Kinetics of inhibition of MAO-B by N-(2-aminoethyl)-p-chlorobenzamide (Ro 16-6491) and analogues. J Neural Transm Suppl. 1994;41:307-11. PubMed PMID: 7931243.
3. Annan N, Silverman RB. New analogues of N-(2-aminoethyl)-4-chlorobenzamide (Ro 16-6491). Some of the most potent monoamine oxidase-B inactivators. J Med Chem. 1993 Nov 26;36(24):3968-70. PubMed PMID: 8254625.
4. Cesura AM, Imhof R, Muggli-Maniglio D, Picotti GB, Da Prada M. Characterization of [3H]Ro 16-6491 binding to digitonin solubilized monoamine oxidase-B and purification of the enzyme from human platelets by affinity chromatography. Biochem Pharmacol. 1990 Jan 1;39(1):216-20. PubMed PMID: 2297358.