Ro 16-8714
| Code | Size | Price |
|---|
| TAR-T28560-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T28560-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T28560-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Ro 16-8714 is an agonist of beta-adrenoreceptor with antihyperglycemic and thermogenic properties.
CAS:
90505-66-1
Formula:
C27H32N2O3
Molecular Weight:
432.564
Purity:
0.98
SMILES:
CC(CCc1ccc(cc1)C(N)=O)N(CC(O)c1ccccc1)CC(O)c1ccccc1
References
1. Revelli JP, Muzzin P, Giacobino JP. Modulation in vivo of beta-adrenergic-receptor subtypes in rat brown adipose tissue by the thermogenic agonist Ro 16-8714. Biochem J. 1992 Sep 15;286 ( Pt 3):743-6. PubMed PMID: 1358062; PubMed Central PMCID: PMC1132966.
2. Ferr? P, P?nicaud L, Hitier Y, Meier M, Girard J. Hypoglycemic effects of a beta-agonist, Ro 16-8714, in streptozotocin-diabetic rats: decreased hepatic glucose production and increased glucose utilization in oxidative muscles. Metabolism. 1992 Feb;41(2):180-3. PubMed PMID: 1346545.
3. Muzzin P, Revelli JP, Ricquier D, Meier MK, Assimacopoulos-Jeannet F, Giacobino JP. The novel thermogenic beta-adrenergic agonist Ro 16-8714 increases the interscapular brown-fat beta-receptor-adenylate cyclase and the uncoupling-protein mRNA level in obese (fa/fa) Zucker rats. Biochem J. 1989 Aug 1;261(3):721-4. PubMed PMID: 2572217; PubMed Central PMCID: PMC1138890.
4. Henny C, B?ckert A, Schutz Y, J?quier E, Felber JP. Comparison of thermogenic activity induced by the new sympathomimetic Ro 16-8714 between normal and obese subjects. Int J Obes. 1988;12(3):227-36. PubMed PMID: 2899062.