Ro 23-7014
| Code | Size | Price |
|---|
| TAR-T28572-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Ro 23-7014, a new thiazepinone Ca2+ channel antagonist, has high affinity for peripheral (Type A) receptors.
CAS:
113714-78-6
Formula:
C48H63N9O16S4
Molecular Weight:
1150.32
Purity:
0.98
SMILES:
CSCC[C@H](NC(=O)[C@@H](N)Cc1ccc(OS(O)(=O)=O)cc1)C(=O)NCC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCSC)C(=O)N[C@@H]([C@@H](C)OS(O)(=O)=O)C(=O)N(C)[C@](Cc1ccccc1)(C(C)=O)C(N)=O
References
1. Sordahl LA, Rex KA, Benedict CR. In vivo inhibition of platelet aggregation and occlusive coronary thrombus formation by a new calcium antagonist (R023-6152). J Cardiovasc Pharmacol. 1991 Oct;18(4):504-10. PubMed PMID: 1724526.
2. Medh JD, Rex KA, Benedict CR, Sordahl LA. In vitro and in vivo effects of R023-6152 on heart mitochondrial calcium and energy metabolism. J Cardiovasc Pharmacol. 1991 Oct;18(4):473-7. PubMed PMID: 1724522.
3. Folkers HB, van Zwienen JC, Boer P, Kleinbloesem CH, Geyskes GG. Hemodynamic effects of Ro 23-6152 in patients with essential hypertension. Eur J Clin Pharmacol. 1991;41(4):307-11. PubMed PMID: 1804644.