Ro 31-8472
Code | Size | Price |
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TAR-T28584-5mg | 5mg | £1,332.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T28584-50mg | 50mg | £2,625.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T28584-100mg | 100mg | £3,524.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
Ro 31-8472 is an angiotensin-converting enzyme (ACE) inhibitor and an analog of cilazaprilat.
CAS:
144284-57-1
Formula:
C20H27N3O6
Molecular Weight:
405.451
Purity:
0.98
SMILES:
OC(=O)[C@H](CCc1ccc(O)cc1)N[C@H]1CCCN2CCC[C@H](N2C1=O)C(O)=O
References
1. Bevilacqua M, Vago T, Rogolino A, Conci F, Santoli E, Norbiato G. Affinity of angiotensin I-converting enzyme (ACE) inhibitors for N- and C-binding sites of human ACE is different in heart, lung, arteries, and veins. J Cardiovasc Pharmacol. 1996 Oct;28(4):494-9. PubMed PMID: 8891872.
2. Vago T, Bevilacqua M, Conci F, Rogolino A, Norbiato G. Pharmacologic data reveal the heterogeneity of angiotensin-converting enzyme according to its source (lung versus heart). Am J Cardiol. 1995 Jun 16;75(18):13F-17F. PubMed PMID: 7778528.
3. Perich RB, Jackson B, Johnston CI. Structural constraints of inhibitors for binding at two active sites on somatic angiotensin converting enzyme. Eur J Pharmacol. 1994 Feb 15;266(3):201-11. PubMed PMID: 8174603.
4. Perich RB, Jackson B, Rogerson F, Mendelsohn FA, Paxton D, Johnston CI. Two binding sites on angiotensin-converting enzyme: evidence from radioligand binding studies. Mol Pharmacol. 1992 Aug;42(2):286-93. PubMed PMID: 1325031.