Ro 31-8830
| Code | Size | Price |
|---|
| TAR-T28586-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T28586-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T28586-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Ro 31-8830, a derivative of Ro 31-8425, has in vivo anti-inflammatory activity.
CAS:
131848-98-1
Formula:
C28H28N4O2
Molecular Weight:
452.558
Purity:
0.98
SMILES:
CN(C)CC1CCn2c(C1)c(C1=C(C(=O)NC1=O)c1cn(C)c3ccccc13)c1ccccc21
References
1. Harmon CS, Nevins TD, Ducote J, Lutz D. Bisindolylmaleimide protein-kinase-C inhibitors delay the decline in DNA synthesis in mouse hair follicle organ cultures. Skin Pharmacol. 1997;10(2):71-8. PubMed PMID: 9257375.
2. Hahn M, Lorez H, Fischer G. The immortalized astroglial cell line RC7 is a new model system for the study of nerve growth factor (NGF) regulation: stimulation by interleukin-1 beta and transforming growth factor-beta 1 is additive and affected differently by dibutyryl cyclic AMP. Glia. 1994 Apr;10(4):286-95. PubMed PMID: 8056439.
3. Mulqueen MJ, Bradshaw D, Davis PD, Elliott L, Griffiths TA, Hill CH, Kumar H, Lawton G, Nixon JS, Sedgwick AD, et al. Oral, anti-inflammatory activity of a potent, selective, protein kinase C inhibitor. Agents Actions. 1992 Sep;37(1-2):85-9. PubMed PMID: 1456183.
4. Nixon JS, Bishop J, Bradshaw D, Davis PD, Hill CH, Elliott LH, Kumar H, Lawton G, Lewis EJ, Mulqueen M, et al. The design and biological properties of potent and selective inhibitors of protein kinase C. Biochem Soc Trans. 1992 May;20(2):419-25. Review. PubMed PMID: 1397642.