Ro 41-5253
Code | Size | Price |
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TAR-T28589-50mg | 50mg | £1,066.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T28589-100mg | 100mg | £1,870.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
Ro 41-5253 is a selective antagonist of RARα. Ro 41-5253 inhibits connexin 43 protein expression induced by retinoic acid in 10T1/2 cells.
CAS:
144092-31-9
Formula:
C28H36O5S
Molecular Weight:
484.65
Purity:
0.98
SMILES:
CCCCCCCOc1cc2c(cc1C(C)=Cc1ccc(cc1)C(O)=O)C(C)(C)CCS2(=O)=O
References
1. Kasimanickam VR, Kasimanickam RK. Retinoic acid signaling biomarkers after treatment with retinoic acid and retinoic acid receptor alpha antagonist (Ro 41-5253) in canine testis: an in vitro organ culture study. Theriogenology. 2013 Jan 1;79(1):10-6. doi: 10.1016/j.theriogenology.2012.09.001. PubMed PMID: 23102850.
2. Toma S, Isnardi L, Raffo P, Riccardi L, Dastoli G, Apfel C, LeMotte P, Bollag W. RARalpha antagonist Ro 41-5253 inhibits proliferation and induces apoptosis in breast-cancer cell lines. Int J Cancer. 1998 Sep 25;78(1):86-94. PubMed PMID: 9724098.