Rutamycin
| Code | Size | Price |
|---|
| TAR-T28626-5mg | 5mg | £2,000.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Rutamycin is a macrolide antibiotic of the oligomycin group obtained from Streptomyces rutgersensis. It inhibits various ATPases and uncouples oxidative phosphorylation from electron transport.
CAS:
1404-59-7
Formula:
C44H72O11
Molecular Weight:
777.049
Purity:
0.98
SMILES:
CC[C@@H]1CC[C@@H]2O[C@]3(CC[C@H](C)[C@H](C[C@@H](C)O)O3)C[C@H](OC(=O)C=C[C@H](C)[C@@H](O)[C@H](C)C(=O)[C@H](C)[C@@H](O)[C@H](C)C(=O)[C@](C)(O)[C@@H](O)[C@H](C)CC=CC=C1)[C@@H]2C
References
1. Lichtor T, Getz GS. Cytoplasmic inheritance of rutamycin resistance in mouse fibroblasts. Proc Natl Acad Sci U S A. 1978 Jan;75(1):324-8. PubMed PMID: 146879; PubMed Central PMCID: PMC411240.
2. Panek JS, Jain NF. Total synthesis of rutamycin B and oligomycin C. J Org Chem. 2001 Apr 20;66(8):2747-56. PubMed PMID: 11304197.
3. Foury F, Tzagoloff A. Localization on mitochondrial DNA of mutations leading to a loss of rutamycin-sensitive adenosine triphosphatase. Eur J Biochem. 1976 Sep;68(1):113-9. PubMed PMID: 134892.
4. White JD, Hanselmann R, Jackson RW, Porter WJ, Ohba Y, Tiller T, Wang S. Total synthesis of rutamycin B, a macrolide antibiotic from Streptomyces aureofaciens. J Org Chem. 2001 Jul 27;66(15):5217-31. PubMed PMID: 11463276.