SCH-50910 free base
| Code | Size | Price |
|---|
| TAR-T28729-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T28729-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T28729-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
SCH-50910 is an antagonist of GABAB receptor.
CAS:
790633-59-9
Formula:
C8H15NO3
Molecular Weight:
173.212
Purity:
0.98
SMILES:
CC1(C)CO[C@H](CC(O)=O)CN1
References
1. Brown JW, Moeller A, Schmidt M, Turner SC, Nimmrich V, Ma J, Rueter LE, van der Kam E, Zhang M. Anticonvulsant effects of structurally diverse GABA(B) positive allosteric modulators in the DBA/2J audiogenic seizure test: Comparison to baclofen and utility as a pharmacodynamic screening model. Neuropharmacology. 2016 Feb;101:358-69. doi: 10.1016/j.neuropharm.2015.10.009. PubMed PMID: 26471422.
2. Minic Z, O'Leary DS, Scislo TJ. NTS adenosine A2a receptors inhibit the cardiopulmonary chemoreflex control of regional sympathetic outputs via a GABAergic mechanism. Am J Physiol Heart Circ Physiol. 2015 Jul 1;309(1):H185-97. doi: 10.1152/ajpheart.00838.2014. PubMed PMID: 25910812; PubMed Central PMCID: PMC4491516.
3. Parker DA, Marino V, Ong J. Pharmacological actions of thymol and an analogue at GABAB autoreceptors. Clin Exp Pharmacol Physiol. 2014 Sep;41(9):623-7. doi: 10.1111/1440-1681.12278. PubMed PMID: 25115309.
4. van Nieuwenhuijzen PS, McGregor IS, Chebib M, Hunt GE. Regional Fos-expression induced by ?-hydroxybutyrate (GHB): comparison with ?-butyrolactone (GBL) and effects of co-administration of the GABAB antagonist SCH 50911 and putative GHB antagonist NCS-382. Neuroscience. 2014 Sep 26;277:700-15. doi: 10.1016/j.neuroscience.2014.07.056. PubMed PMID: 25088910.