Selepressin
| Code | Size | Price |
|---|
| TAR-T28745-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Selepressin, an analog of vasopressin, is a potent, selective vasopressin V1a receptor agonist.
CAS:
876296-47-8
Formula:
C46H73N13O11S2
Molecular Weight:
1048.29
Purity:
0.98
SMILES:
CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](N)CSSC[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCC(N)=O)NC1=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(C)C)C(=O)NCC(N)=O
References
1. Stolk RF, van der Poll T, Angus DC, van der Hoeven JG, Pickkers P, Kox M. Potentially Inadvertent Immunomodulation: Norepinephrine Use in Sepsis. Am J Respir Crit Care Med. 2016 Sep 1;194(5):550-8. doi: 10.1164/rccm.201604-0862CP. PubMed PMID: 27398737.
2. Heming N, Lamothe L, Ambrosi X, Annane D. Emerging drugs for the treatment of sepsis. Expert Opin Emerg Drugs. 2016;21(1):27-37. doi: 10.1517/14728214.2016.1132700. Review. PubMed PMID: 26751198.
3. Asfar P, Russell JA, Tuckermann J, Radermacher P. Selepressin in Septic Shock: A Step Toward Decatecholaminization? Crit Care Med. 2016 Jan;44(1):234-6. doi: 10.1097/CCM.0000000000001441. PubMed PMID: 26672929.
4. He X, Su F, Taccone FS, Laporte R, Kj?lbye AL, Zhang J, Xie K, Moussa MD, Reinheimer TM, Vincent JL. A Selective V(1A) Receptor Agonist, Selepressin, Is Superior to Arginine Vasopressin and to Norepinephrine in Ovine Septic Shock. Crit Care Med. 2016 Jan;44(1):23-31. doi: 10.1097/CCM.0000000000001380. PubMed PMID: 26496451; PubMed Central PMCID: PMC4684247.