Siccanin
| Code | Size | Price |
|---|
| TAR-T28776-5mg | 5mg | £1,044.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Siccanin is an antifungal antibiotic with antidermatophytic properties.
CAS:
22733-60-4
Formula:
C22H30O3
Molecular Weight:
342.479
Purity:
0.98
SMILES:
[H][C@]12OC[C@@]34CCCC(C)(C)[C@]3([H])CC[C@](C)(Oc3cc(C)cc(O)c13)[C@]24[H]
References
1. Bellotti MG, Riviera L. Siccanin: a new antifungal antibiotic with antidermatophytic properties. In vitro studies. Chemioterapia. 1985 Dec;4(6):431-3. PubMed PMID: 3830412.
2. Mogi T, Kawakami T, Arai H, Igarashi Y, Matsushita K, Mori M, Shiomi K, Omura S, Harada S, Kita K. Siccanin rediscovered as a species-selective succinate dehydrogenase inhibitor. J Biochem. 2009 Sep;146(3):383-7. doi: 10.1093/jb/mvp085. Epub 2009 Jun 8. PubMed PMID: 19505951.
3. Trost BM, Shen HC, Surivet JP. An enantioselective biomimetic total synthesis of (-)-siccanin. Angew Chem Int Ed Engl. 2003 Aug 25;42(33):3943-7. PubMed PMID: 12949876.
4. Trost BM, Shen HC, Surivet JP. Biomimetic enantioselective total synthesis of (-)-siccanin via the Pd-catalyzed asymmetric allylic alkylation (AAA) and sequential radical cyclizations. J Am Chem Soc. 2004 Oct 6;126(39):12565-79. PubMed PMID: 15453789.