Silicon Phthalocyanine 4
| Code | Size | Price |
|---|
| TAR-T28777-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Silicon Phthalocyanine 4 is a drug with anti-cutaneous neoplasms activity.
CAS:
135719-28-7
Formula:
C39H35N9O2Si2
Molecular Weight:
717.94
Purity:
0.98
SMILES:
CN(C)CCC[Si](C)(C)O[Si]1(O)n2c3N=C4N=C(N=c5n1c(=NC1=NC(=N/c2c2ccccc32)c2ccccc12)c1ccccc51)c1ccccc41
References
1. Dimaano ML, Rozario C, Nerandzic MM, Donskey CJ, Lam M, Baron ED. The photodynamic antibacterial effects of silicon phthalocyanine (Pc) 4. Int J Mol Sci. 2015 Apr 8;16(4):7851-60. doi: 10.3390/ijms16047851. PubMed PMID: 25856680; PubMed Central PMCID: PMC4425053.
2. Master AM, Livingston M, Oleinick NL, Sen Gupta A. Optimization of a nanomedicine-based silicon phthalocyanine 4 photodynamic therapy (Pc 4-PDT) strategy for targeted treatment of EGFR-overexpressing cancers. Mol Pharm. 2012 Aug 6;9(8):2331-8. doi: 10.1021/mp300256e. PubMed PMID: 22775587; PubMed Central PMCID: PMC3498539.
3. Hutnick MA, Ahsanuddin S, Guan L, Lam M, Baron ED, Pokorski JK. PEGylated Dendrimers as Drug Delivery Vehicles for the Photosensitizer Silicon Phthalocyanine Pc 4 for Candidal Infections. Biomacromolecules. 2017 Feb 13;18(2):379-385. doi: 10.1021/acs.biomac.6b01436. PubMed PMID: 28117573.
4. Soler DC, Ohtola J, Sugiyama H, Rodriguez ME, Han L, Oleinick NL, Lam M, Baron ED, Cooper KD, McCormick TS. Activated T cells exhibit increased uptake of silicon phthalocyanine Pc 4 and increased susceptibility to Pc 4-photodynamic therapy-mediated cell death. Photochem Photobiol Sci. 2016 Jun 8;15(6):822-31. doi: 10.1039/c6pp00058d. PubMed PMID: 27161819; PubMed Central PMCID: PMC4928582.